1) Cat. No.: TRC-P217477; 2) Chemical Name: PD-123319-d6 Bis(trifluoroacetate) Salt Hydrate; 3) CAS No.: ; 4) Mol. Formula: C31H26D6N4O32C2HF3O2xH2O; 5) Mol. Weight: 742.69; 6) Packing Size: 1mg / 10mg; 7) Appearence: ; 8) Application Notes: A labelled selective and potent non-peptide angiotensin II type 2 (AT2) receptor antagonist. Potential treatment of cardiac hypertrophy as blockage of AT2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation. Studies show that it has protective effect against tumor necrosis factor-α-induced damage to human renal proximal tubular epithelial cells; 9) Synonym: (6S)-1-[[4-(Dimethylamino-d6)-3-methylphenyl]methyl]-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic Acid Bis(trifluoroacetate) Salt Hydrate; (S)-(+)-PD 123319-d6 Bis(trifluoroacetate) Salt Hydrate; ; 10) Solubility: ; 11) Storage condition: ; 12) References: Carmeiros-Ramos, M.S. et al.: Bas. Res, Cardiol., 105, 325 (2010); Kagawa, T. et al.: Nephrol., 13, 309 (2008); Cohen, E.P. et al.: Transl. Res., 150, 106 (2007);